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Enhanced interlaminar excitation or reduced superficial layer inhibition in neocortex generates different spike-and-wave-like electrographic events in vitro

Acute in vitro models have revealed a great deal of information about mechanisms underlying many types of epileptiform activity. However, few examples exist that shed light on spike-and-wave (SpW) patterns of pathological activity. SpW are seen in many epilepsy syndromes, both generalized and focal,...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Hall, Stephen P., Traub, Roger D., Adams, Natalie E., Cunningham, Mark O., Schofield, Ian, Jenkins, Alistair J., Whittington, Miles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866469/
https://ncbi.nlm.nih.gov/pubmed/28954894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00516.2017
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