High-content screening assay-based discovery of paullones as novel podocyte-protective agents

Podocyte dysfunction and loss is an early event and a hallmark of proteinuric kidney diseases. A podocyte’s normal function is maintained via its unique cellular architecture that relies on an intracellular network of filaments, including filamentous actin (F-actin) and microtubules, that provides m...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Lee, Ha Won, Arif, Ehtesham, Altintas, Mehmet M., Quick, Kevin, Maheshwari, Shrey, Plezia, Alexandra, Mahmood, Aqsa, Reiser, Jochen, Nihalani, Deepak, Gupta, Vineet
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866451/
https://ncbi.nlm.nih.gov/pubmed/29046299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00338.2017
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