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Hypoxia Inducible Factor 1α Plays a Key Role in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Rats

BACKGROUND: Limb remote ischemic preconditioning (RIPC) protects against brain injury induced by stroke, but the underlying protective mechanisms remain unknown. As hypoxia inducible factor 1α (HIF‐1α) is neuroprotective in stroke and mediates neuroinflammation, we tested the hypothesis that HIF‐1α...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Yang, Jian, Liu, Cuiying, Du, Xiangnan, Liu, Menglei, Ji, Xunming, Du, Huishan, Zhao, Heng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866324/
https://ncbi.nlm.nih.gov/pubmed/29478025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007589
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