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Synergistic anticancer effects of ruxolitinib and calcitriol in estrogen receptor-positive, human epidermal growth factor receptor 2-positive breast cancer cells

The Janus kinase (JAK)1 and JAK2 inhibitor, ruxolitinib, and the active form of vitamin D (calcitriol) were previously reported to possess anticancer effects in breast cancer. The present study investigated the combined effects of ruxolitinib and calcitriol on an estrogen receptor (ER)-positive, hum...

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Publicat a:Mol Med Rep
Autors principals: Lim, Seung Taek, Jeon, Ye Won, Gwak, Hongki, Kim, Se Young, Suh, Young Jin
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865997/
https://ncbi.nlm.nih.gov/pubmed/29436642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8580
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