Glucosylceramide synthase regulates the proliferation and apoptosis of liver cells in vitro by Bcl-2/Bax pathway

Our previous study found that glucosylceramide, a type of sphingolipids, was associated with liver inflammation and fibrosis. Glucosylceramide is generated by glucosylceramide synthase (GCS), which is encoded by the UDP-glucose ceramide glucosyltransferase (UGCG) gene. GCS is a key enzyme to regulat...

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Vydáno v:Mol Med Rep
Hlavní autoři: Li, Jun-Feng, Zheng, Su-Jun, Wang, Li-Li, Liu, Shuang, Ren, Feng, Chen, Yu, Bai, Li, Liu, Mei, Duan, Zhong-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865865/
https://ncbi.nlm.nih.gov/pubmed/28944894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7580
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