Development of an improved RT-qPCR Assay for detection of Japanese encephalitis virus (JEV) RNA including a systematic review and comprehensive comparison with published methods

BACKGROUND: Japanese encephalitis virus (JEV) is a major cause of encephalitis in Asia, and the commonest cause of mosquito-borne encephalitis worldwide. Detection of JEV RNA remains challenging due to the characteristic brief and low viraemia, with 0–25% of patients positive, and the mainstay of di...

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Udgivet i:PLoS One
Main Authors: Bharucha, Tehmina, Sengvilaipaseuth, Onanong, Vongsouvath, Manivanh, Vongsouvath, Malavanh, Davong, Viengmon, Panyanouvong, Phonepasith, Piorkowski, Géraldine, Garson, Jeremy A., Newton, Paul N., de Lamballerie, Xavier, Dubot-Pérès, Audrey
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865736/
https://ncbi.nlm.nih.gov/pubmed/29570739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194412
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