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Orthotopic hepatic cancer: radiofrequency hyperthermia-enhanced intratumoral herpes simplex virus-thymidine kinase gene therapy

PURPOSE: To validate the feasibility of using interventional radiofrequency hyperthermia(RFH) to enhance herpes simplex virus-thymidine kinase (HSV-TK)/ganciclovir (GCV) gene therapy of rat orthotopic hepatic cancer. MATERIAL AND METHODS: Rat hepatocellular carcinoma cells (MCA-RH-7777) were transdu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xiong, Fu, Zhang, Feng, Jin, Yin, Weng, Qiaoyou, Song, Jingjing, Zhou, Guofeng, Shin, David, Zheng, Chuansheng, Yang, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865656/
https://ncbi.nlm.nih.gov/pubmed/29581830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23586
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