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Prostate-specific PTen deletion in mice activates inflammatory microRNA expression pathways in the epithelium early in hyperplasia development

PTen loss is one of the most frequent events in prostate cancer both at the initiation stage and during late stage metastatic development. The mouse model of prostate-specific probasin-mediated Pten deletion leads to prostate intraepithelial neoplasia (PIN) leading to adenocarcinoma. Using this mode...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Dart, D. Alwyn, Uysal-Onganer, Pinar, Jiang, W. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865543/
https://ncbi.nlm.nih.gov/pubmed/29284790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0007-5
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