A New 2-Step Acceleration Protocol Using a Histone Deacetylase Inhibitor to Generate Insulin-Producing Cells From Adipose-Derived Mesenchymal Stem Cells

OBJECTIVES: We aimed to develop a simple protocol for deriving insulin-producing cells (IPCs) from adipose-derived mesenchymal stem cells (ADSCs). We established a 2-step creation method and an acceleration strategy with a histone deacetylase inhibitor that promoted a pro–endocrine pancreatic lineag...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pancreas
Prif Awduron: Ikemoto, Tetsuya, Feng, Rui, Shimada, Mitsuo, Saito, Yu, Iwahashi, Shuichi, Morine, Yuji, Imura, Satoru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2018
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865483/
https://ncbi.nlm.nih.gov/pubmed/29517636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000001017
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