Tocilizumab, tacrolimus and methotrexate for the prevention of acute graft-versus-host disease: low incidence of lower gastrointestinal tract disease

We conducted a phase 2 study in which patients undergoing allogeneic hematopoietic stem cell transplantation received tocilizumab in addition to standard immune suppression with tacrolimus and methotrexate for graft-versus-host disease prophylaxis. Thirty-five patients were enrolled between January...

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Udgivet i:Haematologica
Main Authors: Drobyski, William R., Szabo, Aniko, Zhu, Fenlu, Keever-Taylor, Carolyn, Hebert, Kyle M., Dunn, Renee, Yim, Sharon, Johnson, Bryon, D’Souza, Anita, Eapen, Mary, Fenske, Timothy S., Hari, Parameswaran, Hamadani, Mehdi, Horowitz, Mary M., Rizzo, J. Douglas, Saber, Wael, Shah, Nirav, Shaw, Bronwen, Pasquini, Marcelo
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865423/
https://ncbi.nlm.nih.gov/pubmed/29351985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.183434
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