Functionalised Carbon Nanotubes Enhance Brain Delivery of Amyloid-Targeting Pittsburgh Compound B (PiB)-Derived Ligands

Alzheimer's disease (AD) is a neurodegenerative disorder characterised by brain accumulation of toxic protein aggregates, including extracellular amyloid beta (Aβ) plaques, inflammation, neuronal death and progressive cognitive dysfunction. Current diagnostic modalities, based on cognitive test...

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Detalhes bibliográficos
Publicado no:Nanotheranostics
Main Authors: Costa, Pedro Miguel, Wang, Julie Tzu-Wen, Morfin, Jean-François, Khanum, Tamanna, To, Wan, Sosabowski, Jane, Tóth, Eva, Al-Jamal, Khuloud T
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865270/
https://ncbi.nlm.nih.gov/pubmed/29577020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ntno.23125
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