Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction

Epigenetic modulators play critical roles in reprogramming of cellular functions, emerging as a new class of promising therapeutic targets. Nuclear receptor binding SET domain protein 3 (NSD3) is a member of the lysine methyltransferase family. Interestingly, the short isoform of NSD3 without the me...

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Publicat a:Assay Drug Dev Technol
Autors principals: Xiong, Jinglin, Pecchi, Valentina Gonzalez, Qui, Min, Ivanov, Andrey A., Mo, Xiulei, Niu, Qiankun, Chen, Xiang, Fu, Haian, Du, Yuhong
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2018
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865254/
https://ncbi.nlm.nih.gov/pubmed/29634317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2017.835
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