Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes

Assessing the phenotypic diversity underlying tumour progression requires the identification of variations in the respective molecular interaction networks. Here we report proof-of-concept for a platform called poly-ligand profiling (PLP) that surveys these system states and distinguishes breast can...

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發表在:Nat Commun
Main Authors: Domenyuk, Valeriy, Gatalica, Zoran, Santhanam, Radhika, Wei, Xixi, Stark, Adam, Kennedy, Patrick, Toussaint, Brandon, Levenberg, Symon, Wang, Jie, Xiao, Nianqing, Greil, Richard, Rinnerthaler, Gabriel, Gampenrieder, Simon P., Heimberger, Amy B., Berry, Donald A., Barker, Anna, Quackenbush, John, Marshall, John L., Poste, George, Vacirca, Jeffrey L., Vidal, Gregory A., Schwartzberg, Lee S., Halbert, David D., Voss, Andreas, Magee, Daniel, Miglarese, Mark R., Famulok, Michael, Mayer, Günter, Spetzler, David
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865185/
https://ncbi.nlm.nih.gov/pubmed/29572535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03631-z
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