Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes

Assessing the phenotypic diversity underlying tumour progression requires the identification of variations in the respective molecular interaction networks. Here we report proof-of-concept for a platform called poly-ligand profiling (PLP) that surveys these system states and distinguishes breast can...

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Published in:Nat Commun
Main Authors: Domenyuk, Valeriy, Gatalica, Zoran, Santhanam, Radhika, Wei, Xixi, Stark, Adam, Kennedy, Patrick, Toussaint, Brandon, Levenberg, Symon, Wang, Jie, Xiao, Nianqing, Greil, Richard, Rinnerthaler, Gabriel, Gampenrieder, Simon P., Heimberger, Amy B., Berry, Donald A., Barker, Anna, Quackenbush, John, Marshall, John L., Poste, George, Vacirca, Jeffrey L., Vidal, Gregory A., Schwartzberg, Lee S., Halbert, David D., Voss, Andreas, Magee, Daniel, Miglarese, Mark R., Famulok, Michael, Mayer, Günter, Spetzler, David
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865185/
https://ncbi.nlm.nih.gov/pubmed/29572535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03631-z
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