Contribution of germline deleterious variants in the RAD51 paralogs to breast and ovarian cancers

RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3) have recently been involved in breast and ovarian cancer predisposition: RAD51B, RAD51C, and RAD51D in ovarian cancer, RAD51B and XRCC2 in breast cancer. The aim of this study was to estimate the contribution of deleterious variants in the fi...

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Publicado no:Eur J Hum Genet
Main Authors: Golmard, Lisa, Castéra, Laurent, Krieger, Sophie, Moncoutier, Virginie, Abidallah, Khadija, Tenreiro, Henrique, Laugé, Anthony, Tarabeux, Julien, Millot, Gael A., Nicolas, André, Laé, Marick, Abadie, Caroline, Berthet, Pascaline, Polycarpe, Florence, Frébourg, Thierry, Elan, Camille, de Pauw, Antoine, Gauthier-Villars, Marion, Buecher, Bruno, Stern, Marc-Henri, Stoppa-Lyonnet, Dominique, Vaur, Dominique, Houdayer, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865182/
https://ncbi.nlm.nih.gov/pubmed/29255180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-017-0021-2
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