Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

Successive rounds of chemical modification in three generations of benzopyran molecules have shown to select for different mechanisms of actions and progressive increases in anti-cancer activity. In this study, we investigated the mechanism of action of the third-generation benzopyran compounds, TRX...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Stevenson, Alexander J., Ager, Eleanor I., Proctor, Martina A., Škalamera, Dubravka, Heaton, Andrew, Brown, David, Gabrielli, Brian G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865165/
https://ncbi.nlm.nih.gov/pubmed/29572477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22882-w
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