RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts

The fusion of villous cytotrophoblasts into the multinucleated syncytiotrophoblast is critical for the essential functions of the mammalian placenta. Using RNA-Seq gene expression and quantitative protein expression, we identified genes and their cognate proteins which are coordinately up- or down-r...

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Publicat a:Sci Rep
Autors principals: Azar, Christopher, Valentine, Mark, Trausch-Azar, Julie, Druley, Todd, Nelson, D. Michael, Schwartz, Alan L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865118/
https://ncbi.nlm.nih.gov/pubmed/29572450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23379-2
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