Cell Cycle Arrest and Apoptosis Induced by Porphyromonas gingivalis Require Jun N-Terminal Protein Kinase- and p53-Mediated p38 Activation in Human Trophoblasts

Porphyromonas gingivalis, a periodontal pathogen, has been implicated as a causative agent of preterm delivery of low-birth-weight infants. We previously reported that P. gingivalis activated cellular DNA damage signaling pathways and ERK1/2 that lead to G(1) arrest and apoptosis in extravillous tro...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Inaba, Hiroaki, Amano, Atsuo, Lamont, Richard J., Murakami, Yukitaka, Matsumoto-Nakano, Michiyo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865039/
https://ncbi.nlm.nih.gov/pubmed/29339463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00923-17
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