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Dual binding in cohesin-dockerin complexes: the energy landscape and the role of short, terminal segments of the dockerin module

The assembly of the polysaccharide degradating cellulosome machinery is mediated by tight binding between cohesin and dockerin domains. We have used an empirical model known as FoldX as well as molecular mechanics methods to determine the free energy of binding between a cohesin and a dockerin from...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Wojciechowski, Michał, Różycki, Bartosz, Huy, Pham Dinh Quoc, Li, Mai Suan, Bayer, Edward A., Cieplak, Marek
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864761/
https://ncbi.nlm.nih.gov/pubmed/29568013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23380-9
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