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Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model

BACKGROUND: Hepatic cytochrome P450 (CYP) isoforms, CYP1A2, is one of important enzymes for many drugs metabolism. Studies have confirmed that sustained hypoxia can influence the expression of hepatic CYP, including CYP1A2. The impact of chronic intermittent hypoxia (CIH), a marked characteristic of...

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Bibliografiske detaljer
Udgivet i:J Thorac Dis
Main Authors: Zhang, Xiao-Bin, Zeng, Yi-Ming, Chen, Xiao-Yang, Zhang, Yi-Xiang, Ding, Jin-Zhen, Xue, Cheng
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864663/
https://ncbi.nlm.nih.gov/pubmed/29607154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2017.12.106
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