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Modest enhancement of sensory axon regeneration in the sciatic nerve with conditional co-deletion of PTEN and SOCS3 in the dorsal root ganglia of adult mice

Axons within the peripheral nervous system are capable of regeneration, but full functional recovery is rare. Recent work has shown that conditional deletion of two key signaling inhibitors of the PI3K and Jak/Stat pathways—phosphatase and tensin homolog (PTEN) and suppressor of cytokine signaling-3...

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Publicat a:Exp Neurol
Autors principals: Gallaher, Zachary R., Steward, Oswald
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864562/
https://ncbi.nlm.nih.gov/pubmed/29458059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.02.012
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