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RGC-32 deficiency protects endothelial cell from inflammation and attenuates atherosclerosis

OBJECTIVE: The objective of this study is to determine the role and underlying mechanisms of response gene to complement 32 (RGC-32) in atherogenesis. APPROACH AND RESULTS: RGC-32 was mainly expressed in endothelial cells (ECs) of atherosclerotic lesions in both apolipoprotein E-deficient (ApoE(−/−)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Cui, Xiao-Bing, Luan, Jun-Na, Dong, Kun, Chen, Sisi, Wang, Yongyi, Watford, Wendy T., Chen, Shi-You
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864544/
https://ncbi.nlm.nih.gov/pubmed/29449334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310656
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