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Development of Tizanidine HCl-Meloxicam loaded mucoadhesive buccal films: In-vitro and in-vivo evaluation

The purpose of the study was to develop Tizanidine HCl (TZN) and Meloxicam (MLX) loaded bilayer mucoadhesive films intended for buccal administration, aiming to enhance the bioavailability. Bilayer films were prepared by solvent evaporation technique selecting arabinoxylan (ARX) as a sustained relea...

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Publicat a:PLoS One
Autors principals: Zaman, Muhammad, Hanif, Muhammad, Shaheryar, Zaib Ali
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864138/
https://ncbi.nlm.nih.gov/pubmed/29566073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194410
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