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Closely related, yet unique: Distinct homo- and heterodimerization patterns of G protein coupled chemokine receptors and their fine-tuning by cholesterol

Chemokine receptors, a subclass of G protein coupled receptors (GPCRs), play essential roles in the human immune system, they are involved in cancer metastasis as well as in HIV-infection. A plethora of studies show that homo- and heterodimers or even higher order oligomers of the chemokine receptor...

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Pubblicato in:PLoS Comput Biol
Autori principali: Gahbauer, Stefan, Pluhackova, Kristyna, Böckmann, Rainer A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864085/
https://ncbi.nlm.nih.gov/pubmed/29529028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006062
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