Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition

Despite the increasingly recognized importance of the tumor microenvironment (TME) as a regulator of tumor progression, only few in vitro models have been developed to systematically study the effects of TME on tumor behavior in a controlled manner. Here we developed a three-dimensional (3D) in vitr...

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Bibliographic Details
Published in:PLoS One
Main Authors: Herrera-Perez, R. Marisol, Voytik-Harbin, Sherry L., Sarkaria, Jann N., Pollok, Karen E., Fishel, Melissa L., Rickus, Jenna L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863989/
https://ncbi.nlm.nih.gov/pubmed/29566069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194183
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