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The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells

Our quest to isolate and characterize natural products with in vitro solid tumor selectivity is driven by access to repositories of Indo-Pacific sponge extracts. In this project an extract of a species of Haplosclerida sponge obtained from the US NCI Natural Products Repository displayed, by in vitr...

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Detalhes bibliográficos
Publicado no:Tetrahedron
Main Authors: Lorig-Roach, Nicholas, Hamkins-Indik, Frances, Johnson, Tyler A., Tenney, Karen, Valeriote, Frederick A., Crews, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863921/
https://ncbi.nlm.nih.gov/pubmed/29576661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2017.11.029
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