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Stem cell properties of human clonal salivary gland stem cells are enhanced by three-dimensional priming culture in nanofibrous microwells

BACKGROUND: Three-dimensional (3D) cultures recapitulate the microenvironment of tissue-resident stem cells and enable them to modulate their properties. We determined whether salivary gland-resident stem cells (SGSCs) are primed by a 3D spheroid culture prior to treating irradiation-induced salivar...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Shin, Hyun-Soo, Lee, Songyi, Hong, Hye Jin, Lim, Young Chang, Koh, Won-Gun, Lim, Jae-Yol
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863805/
https://ncbi.nlm.nih.gov/pubmed/29566770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0829-x
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