Interplay Between Capsule Expression and Uracil Metabolism in Streptococcus pneumoniae D39

Pyrimidine nucleotides play an important role in the biosynthesis of activated nucleotide sugars (NDP-sugars). NDP-sugars are the precursors of structural polysaccharides in bacteria, including capsule, which is a major virulence factor of the human pathogen S. pneumoniae. In this work, we identifie...

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Udgivet i:Front Microbiol
Main Authors: Carvalho, Sandra M., Kloosterman, Tomas G., Manzoor, Irfan, Caldas, José, Vinga, Susana, Martinussen, Jan, Saraiva, Lígia M., Kuipers, Oscar P., Neves, Ana R.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863508/
https://ncbi.nlm.nih.gov/pubmed/29599757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00321
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