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Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene

BACKGROUND: Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of Helicobacter pylori eradication. Although the molecular mechanism of CLR resistance has been clearly understood in H. pylori, it is lack of evidence of other genes involved in drug resistance. Furthe...

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Detalhes bibliográficos
Publicado no:Ann Clin Microbiol Antimicrob
Main Authors: Chen, Jiaoe, Ye, Liping, Jin, Liangmin, Xu, Xuehua, Xu, Peisong, Wang, Xianjun, Li, Hongzhang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863438/
https://ncbi.nlm.nih.gov/pubmed/29562911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12941-018-0259-8
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