Lactate as a Potential Biomarker of Sepsis in a Rat Cecal Ligation and Puncture Model

We attempted to investigate whether blood lactate is a useful biomarker for sepsis in a rat cecal ligation and puncture (CLP) model. Male Sprague-Dawley rats underwent approximately 75% cecum ligation and two punctures to induce high-grade sepsis. A lactate of 1.64 mmol/L (Youden score of 0.722) was...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Zhai, Xiaozhu, Yang, Zhengfei, Zheng, Guanghui, Yu, Tao, Wang, Peng, Liu, Xuefen, Ling, Qin, Jiang, Longyuan, Tang, Wanchun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863333/
https://ncbi.nlm.nih.gov/pubmed/29706801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8352727
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