A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and transmission of the malaria parasite Plasmodium falciparum during blood stage infection. Here, we use ChIP sequencing to demonstrate that sporozoites from mosquito salivary glands expand heterochromatin at subte...

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Udgivet i:Cell Rep
Main Authors: Zanghì, Gigliola, Vembar, Shruthi S., Baumgarten, Sebastian, Ding, Shuai, Guizetti, Julien, Bryant, Jessica M., Mattei, Denise, Jensen, Anja T.R., Rénia, Laurent, Goh, Yun Shan, Sauerwein, Robert, Hermsen, Cornelus C., Franetich, Jean-François, Bordessoulles, Mallaury, Silvie, Olivier, Soulard, Valérie, Scatton, Olivier, Chen, Patty, Mecheri, Salah, Mazier, Dominique, Scherf, Artur
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863040/
https://ncbi.nlm.nih.gov/pubmed/29539423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.075
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