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Higher aminopeptidase activity determined by electroosmotic push-pull perfusion contributes to selective vulnerability of the hippocampal CA1 region to oxygen glucose deprivation

It has been known for over a century that the hippocampus, the center for learning and memory in the brain, is selectively vulnerable to ischemic damage, with the CA1 being more vulnerable than the CA3. It is also known that leucine enkephalin, or YGGFL, is neuroprotective. We hypothesized that the...

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Vydáno v:ACS Chem Neurosci
Hlavní autoři: Ou, Yangguang, Weber, Stephen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862982/
https://ncbi.nlm.nih.gov/pubmed/29078045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00326
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