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Flexible pseudotyping of retrovirus using recombinase-mediated cassette exchange

OBJECTIVE: Develop an engineered cell line containing two flexible gene expression systems enabling the continuous production of tailor-made recombinant gammaretrovirus with predictable productivities through targeted integration. RESULTS: Dual-FLEX cells (dFLEX) contain two independent recombinase-...

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Détails bibliographiques
Publié dans:Biotechnol Lett
Auteurs principaux: Soares, Hugo R., Almeida, Ana I., Tomás, Hélio A., Alves, Paula M., Coroadinha, Ana S.
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862940/
https://ncbi.nlm.nih.gov/pubmed/29353442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10529-018-2515-6
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