Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation

Phosphoinositides (PIs) play important roles in numerous membrane-based cellular activities. However, their involvement in the mechanism of T cell receptor (TCR) signal transduction across the plasma membrane (PM) is poorly defined. Here, we investigate their role, and in particular that of phosphat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chouaki Benmansour, Nassima, Ruminski, Kilian, Sartre, Anne-Marie, Phelipot, Marie-Claire, Salles, Audrey, Bergot, Elise, Wu, Ambroise, Chicanne, Gaëtan, Fallet, Mathieu, Brustlein, Sophie, Billaudeau, Cyrille, Formisano, Anthony, Mailfert, Sébastien, Payrastre, Bernard, Marguet, Didier, Brasselet, Sophie, Hamon, Yannick, He, Hai-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862878/
https://ncbi.nlm.nih.gov/pubmed/29563576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23109-8
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