Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2

Bullous pemphigoid (BP), the most frequent autoimmune bullous disorder, is a paradigmatic autoantibody-mediated disease associated with autoantibodies against BP180 (type XVII collagen, Col17). Several animal models have been developed that reflect important clinical and immunological features of hu...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Karsten, Christian M., Beckmann, Tina, Holtsche, Maike M., Tillmann, Jenny, Tofern, Sabrina, Schulze, Franziska S., Heppe, Eva Nina, Ludwig, Ralf J., Zillikens, Detlef, König, Inke R., Köhl, Jörg, Schmidt, Enno
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862877/
https://ncbi.nlm.nih.gov/pubmed/29599777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00488
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