Metabotropic Glutamate(2) Receptors Play a Key Role in Modulating Head Twitches Induced by a Serotonergic Hallucinogen in Mice

There is substantial evidence that glutamate can modulate the effects of 5-hydroxytryptamine(2A) (5-HT(2A)) receptor activation through stimulation of metabotropic glutamate(2/3) (mGlu(2/3)) receptors in the prefrontal cortex. Here we show that constitutive deletion of the mGlu(2) gene profoundly at...

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Vydáno v:Front Pharmacol
Hlavní autoři: Benvenga, Mark J., Chaney, Stephen F., Baez, Melvyn, Britton, Thomas C., Hornback, William J., Monn, James A., Marek, Gerard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862811/
https://ncbi.nlm.nih.gov/pubmed/29599719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00208
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