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C-Reactive Protein As a Mediator of Complement Activation and Inflammatory Signaling in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a devastating neurodegenerative disease affecting millions worldwide. Complement activation, inflammation, and the loss of choroidal endothelial cells have been established as key factors in both normal aging and AMD; however, the exact mechanisms for these...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Chirco, Kathleen R., Potempa, Lawrence A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862805/
https://ncbi.nlm.nih.gov/pubmed/29599782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00539
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