Proline oxidase silencing induces proline-dependent pro-survival pathways in MCF-7 cells

Proline degradation by proline dehydrogenase/proline oxidase (PRODH/POX) contributes to apoptosis or autophagy. The identification of specific pathway of apoptosis/survival regulation is the aim of this study. We generated knocked-down PRODH/POX MCF-7 breast cancer cells (MCF-7(shPRODH/POX)). PRODH/...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Zareba, Ilona, Celinska-Janowicz, Katarzyna, Surazynski, Arkadiusz, Miltyk, Wojciech, Palka, Jerzy
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862612/
https://ncbi.nlm.nih.gov/pubmed/29568391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24466
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