Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia tsutsugamushi Karp

BACKGROUND: Scrub typhus is an important endemic disease in tropical Asia caused by Orientia tsutsugamushi for which no effective broadly protective vaccine is available. The successful evaluation of vaccine candidates requires well-characterized animal models and a better understanding of the immun...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Sunyakumthorn, Piyanate, Somponpun, Suwit J., Im-erbsin, Rawiwan, Anantatat, Tippawan, Jenjaroen, Kemajittra, Dunachie, Susanna J., Lombardini, Eric D., Burke, Robin L., Blacksell, Stuart D., Jones, James W., Mason, Carl J., Richards, Allen L., Day, Nicholas P. J., Paris, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862536/
https://ncbi.nlm.nih.gov/pubmed/29522521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006305
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