Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling

Non-malignant breast epithelial cells cultured in three-dimensional laminin-rich extracellular matrix (lrECM) form well organized, growth-arrested acini, whereas malignant cells form continuously growing disorganized structures. While the mechanical properties of the microenvironment have been shown...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Ricca, Benjamin L, Venugopalan, Gautham, Furuta, Saori, Tanner, Kandice, Orellana, Walter A, Reber, Clay D, Brownfield, Douglas G, Bissell, Mina J, Fletcher, Daniel A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2018
Konular:
Cancer Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862525/
https://ncbi.nlm.nih.gov/pubmed/29560858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26161
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