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Linear-In-Flux-Expressions Methodology: Toward a Robust Mathematical Framework for Quantitative Systems Pharmacology Simulators

Quantitative Systems Pharmacology (QSP) modeling is increasingly used as a quantitative tool for advancing mechanistic hypotheses on the mechanism of action of a drug, and its pharmacological effect in relevant disease phenotypes, to enable linking the right drug to the right patient. Application of...

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Detalhes bibliográficos
Publicado no:Gene Regul Syst Bio
Main Authors: McQuade, Sean T, Abrams, Ruth E, Barrett, Jeffrey S, Piccoli, Benedetto, Azer, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862386/
https://ncbi.nlm.nih.gov/pubmed/29581702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177625017711414
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