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CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells
The ectodomain of the plasma membrane ectoenzyme CD38 functions as both an NAD glycohydrolase and an ADP-ribosyl cyclase by catalyzing, respectively, the conversion of NAD to nicotinamide and ADP-ribose or cyclic ADP-ribose. CD38 is attracting particular attention in cancer therapy. An anti-CD38 mon...
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| Publicado no: | Carcinogenesis |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5862338/ https://ncbi.nlm.nih.gov/pubmed/29228209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx137 |
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