Fibroblast growth factor-2–mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma

In esophageal squamous cell carcinoma (ESCC), a subset of cells defined by high expression of CD44 and low expression of CD24 has been reported to possess characteristics of cancer stem-like cells (CSCs). Novel therapies directly targeting CSCs have the potential to improve prognosis of ESCC patient...

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Bibliographic Details
Published in:Carcinogenesis
Main Authors: Maehara, Osamu, Suda, Goki, Natsuizaka, Mitsuteru, Ohnishi, Shunsuke, Komatsu, Yoshito, Sato, Fumiyuki, Nakai, Masato, Sho, Takuya, Morikawa, Kenichi, Ogawa, Koji, Shimazaki, Tomoe, Kimura, Megumi, Asano, Ayaka, Fujimoto, Yoshiyuki, Ohashi, Shinya, Kagawa, Shingo, Kinugasa, Hideaki, Naganuma, Seiji, Whelan, Kelly A, Nakagawa, Hiroshi, Nakagawa, Koji, Takeda, Hiroshi, Sakamoto, Naoya
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Biology, Genetics and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862278/
https://ncbi.nlm.nih.gov/pubmed/28927233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx095
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