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Variance component score test for time-course gene set analysis of longitudinal RNA-seq data

As gene expression measurement technology is shifting from microarrays to sequencing, the statistical tools available for their analysis must be adapted since RNA-seq data are measured as counts. It has been proposed to model RNA-seq counts as continuous variables using nonparametric regression to a...

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Bibliographic Details
Published in:Biostatistics
Main Authors: Agniel, Denis, Hejblum, Boris P.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862256/
https://ncbi.nlm.nih.gov/pubmed/28334305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxx005
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