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Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation

Celastrol is an anti-inflammatory natural triterpenoid, isolated from the herb Tripterygium wilfordii or thunder god vine. Here, we define mechanisms mediating anti-inflammatory activity of celastrol and demonstrate efficacy of a dietary celastrol supplement for chemoprevention of inflammation-drive...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Barker, Emily C, Kim, Byung-Gyu, Yoon, Ji Hee, Tochtrop, Gregory P, Letterio, John J, Choi, Sung Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862246/
https://ncbi.nlm.nih.gov/pubmed/29069290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx115
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