Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay

Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. Since OT is a peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies. Although studies have shown increased cerebrospinal fluid (CSF) OT levels following IN administration, this does n...

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Udgivet i:Mol Psychiatry
Main Authors: Lee, MR, Scheidweiler, KB, Diao, XX, Akhlaghi, F, Cummins, A, Huestis, MA, Leggio, L, Averbeck, BB
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862033/
https://ncbi.nlm.nih.gov/pubmed/28289281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.27
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