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Ascorbate Protects the Di-Heme Enzyme, MauG, Against Self-Inflicted Oxidative Damage by an Unusual Antioxidant Mechanism

Ascorbate protects MauG from self-inactivation that occurs during the autoreduction of the reactive bis-Fe(IV) state of its diheme cofactor. The mechanism of protection does not involve direct reaction with reactive oxygen species in solution. Instead it binds to MauG and mitigates oxidative damage...

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Detaylı Bibliyografya
Yayımlandı:Biochem J
Asıl Yazarlar: Ma, Zhongxin, Davidson, Victor L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862032/
https://ncbi.nlm.nih.gov/pubmed/28634178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170349
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