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Targeted Delivery of Auristatin-Modified Toxins to Pancreatic Cancer Using Aptamers
Pancreatic cancer is one of the most lethal malignancies. Treatment with the first-line agent, gemcitabine, is often unsuccessful because it, like other traditional chemotherapeutic agents, is non-specific, resulting in off-target effects that necessitate administration of subcurative doses. Alterna...
Enregistré dans:
| Publié dans: | Mol Ther Nucleic Acids |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Gene & Cell Therapy
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5862029/ https://ncbi.nlm.nih.gov/pubmed/29499935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.11.013 |
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