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Sex-dependent Differences in Liver and Gut Metabolomic Profiles With Acarbose and Calorie Restriction in C57BL/6 Mice

Acarbose, an alpha-glucosidase inhibitor used in treating type 2 diabetes, impairs complex carbohydrate digestion and absorption and extends life span in mice (without a requisite reduction in food intake). To assess sex-differential effects coincident with calorie restriction versus a nonrestricted...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gerontol A Biol Sci Med Sci
Prif Awduron: Gibbs, Victoria K, Brewer, Rachel A, Miyasaki, Nathan D, Patki, Amit, Smith, Daniel L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861978/
https://ncbi.nlm.nih.gov/pubmed/28651373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glx127
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