Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations

Life span is a complex trait regulated by multiple genetic and environmental factors; however, the genetic determinants of extreme longevity have been largely unknown. To identify the functional coding variants associated with extreme longevity, we performed an exome-wide association study (EWAS) on...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Tanisawa, Kumpei, Arai, Yasumichi, Hirose, Nobuyoshi, Shimokata, Hiroshi, Yamada, Yoshiji, Kawai, Hisashi, Kojima, Motonaga, Obuchi, Shuichi, Hirano, Hirohiko, Yoshida, Hideyo, Suzuki, Hiroyuki, Fujiwara, Yoshinori, Ihara, Kazushige, Sugaya, Maki, Arai, Tomio, Mori, Seijiro, Sawabe, Motoji, Sato, Noriko, Muramatsu, Masaaki, Higuchi, Mitsuru, Liu, Yao-Wen, Kong, Qing-Peng, Tanaka, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861862/
https://ncbi.nlm.nih.gov/pubmed/27154906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glw074
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